Metformin

Metformin is the first-line oral medication for type 2 diabetes mellitus and the most prescribed antidiabetic drug worldwide. A biguanide class medication, it works primarily by reducing hepatic glucose production, improving insulin sensitivity in peripheral tissues, and modestly reducing intestinal glucose absorption. Metformin is notable for its cardiovascular benefits, weight-neutral to mildly weight-reducing profile, low risk of hypoglycemia, and potential anti-aging properties.